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"Rigaku is the only supplier in the market that can implement the procurement and meet all its specific requirements. Moreover, installation of the new detector system will be accompanied by changes in the geometry of the data collection, to enhance flexibility and offer new capabilities in collecting high quality data from protein crystals to enhance our research and services. The Rigaku 4-circle kappa goniometer which will be purchased together with the detector offers more flexible and efficient data-collection strategies, with \u2018completeness\u2019 in the data-set achievable with the fewest number of data-collection images required. The 4-circle kappa goniometer is most flexible for the optimal measurement of \u2018Friedel pair\u2019 reflections in the same image: therefore, anomalous differences can be measured most accurately and precisely. With the installation of Rigaku 4-circle kappa \u2018Universal Goniometer\u2019 system, the data-collection speeds will be very high (Omega: up to 10\u00b0 per second, Phi: up to 20\u00b0 per second): therefore, optimized for most rapid data-collection and best-matched to the very high brightness of the existing X-ray generator \/ optics and to the zero read-out time \/ shutterless data-collection capabilities of the HyPix-6000HE. Installation of the 4-circle kappa \u2018Universal Goniometer\u2019 system will allow in situ crystal screening and data collection by using the Rigaku XtalCheck-S attachment, which will be purchased under the current procurement along with the HyPix-6000HE. The XtalCheck-S attachment is readily interchangeable on the \u2018Universal Goniometer\u2019 system with the usual \u2018cryo-crystallography\u2019 mode of operation and allows the optical imaging of crystals and collection of X-ray diffraction data on the HyPix-6000HE detector from selected objects (putative protein crystals) in situ in the crystallization plate, therefore, without any disturbance to the crystal in its mother liquor or to the crystallization conditions, etc. The XtalCheck-S is immediately compatible with the 4-circle kappa \u2018Universal Goniometer\u2019 system, above, and with the CrysAlisPro instrument control, data-collection and data-analysis software suite. No modifications will be needed. 5. The XtalCheck-S is a unique device that enables optical imaging, crystal screening and X-ray diffraction data-collection access to all droplets \/ wells of a standard 96-well \u2018SBS\u2019 format crystallization plate: no manual flipping of the crystallization plate is required. "
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