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"Hankinnassa on matalan magneettikent\u00e4n (80 MHz) NMR-spektrometri seerumi- ja virtsan\u00e4ytteiden kvantitatiivisiin metabolisiin analyyseihin ja tutkimuksiin. ",
"",
"Hankintayksik\u00f6n tutkimukseen tarvitaan laite, joka toteuttaa kaikki seuraavat tekniset vaatimukset:",
"1) Laitteen tulee olla kuljetettavissa henkil\u00f6autossa yhden henkil\u00f6n toimesta. Sen tulee painaa alle 75 kg ja olla mitoiltaan pienempi kuin 50 x 50 x 60 cm. Keskeinen osa t\u00e4t\u00e4 tutkimushanketta on mahdollistaa mm. seurantatutkimusten (esim. ravinto- ja liikuntainterventio) n\u00e4ytteiden nopea paikallinen analyysi ja tulosten vuorovaikutteinen k\u00e4ytt\u00f6 meneill\u00e4\u00e4n olevien tutkimusten jatkon suunnittelussa. Perinteinen keskitetty laboratorioanalytiikka ei toimi n\u00e4iss\u00e4 yhteyksiss\u00e4, koska keskitettyjen laboratorioiden aikaikkuna vastaaville analyyseille on viikkoja, usein jopa kuukausia.",
"2) Hankintayksik\u00f6n tutkimus liittyy laajoihin epidemiologisiin aineistoihin, joissa n\u00e4ytteit\u00e4 tyypillisesti analysoidaan useita tuhansia yht\u00e4 tutkimusprojektia kohti. Laitteen tulee n\u00e4in ollen pysty\u00e4 analysoimaan v\u00e4hint\u00e4\u00e4n 12 ihmisen seerumin\u00e4ytett\u00e4 tunnissa; t\u00e4m\u00e4 edellytt\u00e4\u00e4 laitteelta 1H-NMR -sensitiivisyytt\u00e4, joka on v\u00e4hint\u00e4\u00e4n 250.",
"3) Hankintayksik\u00f6n tutkimus fokusoituu ihmisen seerumi- ja virtsan\u00e4ytteisiin, joissa kvantitatiivisia NMR-mittauksia h\u00e4iritsev\u00e4 vesipitoisuus on eritt\u00e4in suuri. Laitteen pit\u00e4\u00e4 pysty\u00e4 ko. h\u00e4iritsev\u00e4n vesisignaalin tarkkaan elektroniseen poistoon; t\u00e4m\u00e4 edellytt\u00e4\u00e4 laitteelta hyv\u00e4\u00e4 resoluutiota, v\u00e4hint\u00e4\u00e4n niin, ett\u00e4 ko. 80 MHz:n kent\u00e4ss\u00e4 saavutetaan NMR-signaalijuovan puoliarvoleveys, joka on pienempi kuin 0.2 Hz.",
"4) Hankittavaa laitetta tullaan k\u00e4ytt\u00e4m\u00e4\u00e4n hyvin erilaisissa tiloissa ja s\u00e4\u00e4olosuhteissa (my\u00f6s eri maissa) ja sen pit\u00e4\u00e4 n\u00e4in ollen toimia ongelmitta laajalla (huone)l\u00e4mp\u00f6tila-alueella. Useinkaan ilmastointia ei ole k\u00e4ytett\u00e4viss\u00e4, joten mittaukset pit\u00e4\u00e4 voida suorittaa ongelmitta l\u00e4mp\u00f6tilan vaihtelualueella +-5 astetta.",
"5) Epidemiologisissa ja kliinisiss\u00e4 tutkimuksissa k\u00e4ytet\u00e4\u00e4n n\u00e4yteputkia ihmisen seerumi- ja virtsan\u00e4ytteiden ker\u00e4\u00e4miseen, s\u00e4ilytt\u00e4miseen ja analysointiin. Laitteen tulee mahdollistaa mittaukset suoraan n\u00e4yteputkista. N\u00e4ytteen injektointiin perustuvat menetelm\u00e4t\/laitteet eiv\u00e4t siis sovellu t\u00e4h\u00e4n k\u00e4ytt\u00f6tarkoitukseen.",
"",
"Suorahankinnan perustelut",
"",
"Hankintamenettelyn\u00e4 on suorahankinta. Peruste suorahankinnalle on hankintalain 1397\/2016 mukainen.",
"",
"40 \u00a7:n mukaiset perusteet:",
"",
"2)\u2002teknisest\u00e4 tai yksinoikeuden suojaamiseen liittyv\u00e4st\u00e4 syyst\u00e4 vain tietty toimittaja voi toteuttaa hankinnan; lis\u00e4edellytyksen\u00e4 on, ett\u00e4 j\u00e4rkevi\u00e4 vaihtoehtoisia tai korvaavia ratkaisuja ei ole eik\u00e4 kilpailun puuttuminen johdu hankinnan ehtojen keinotekoisesta kaventamisesta.",
"",
"Hankintayksik\u00f6n Suomen Akatemian rahoittama tutkimusprojekti edellytt\u00e4\u00e4 ihmisen seerumin ja virtsan kvantitatiivisia metabolisia analyysej\u00e4. Projektiin kiinte\u00e4sti liittyv\u00e4t paikalliset analyysit uuden teknologian matalan magneettikent\u00e4n NMR-laitteella useissa eri paikoissa sijaitsevissa tutkimuslaboratorioissa voidaan toteuttaa ainoastaan, jos kaikki edell\u00e4 mainitut tekniset vaatimukset 1) \u2013 5) toteutuvat.",
"",
"Edell\u00e4 mainittujen laajojen selvitysten perusteella Magritek on ainoa t\u00e4m\u00e4nhetkinen toimittaja, joka valmistaa hankintayksik\u00f6n tarpeiden mukaista laitetta, jolla voidaan mitata paikallisesti ihmisen seerumi- ja virtsan\u00e4ytteit\u00e4 epidemiologisissa tutkimuksissa. Muilla valmistajilla ei ole t\u00e4ll\u00e4 hetkell\u00e4 samanlaista laitetta, joka kaikilta tarvitsemiltamme teknisilt\u00e4 ominaisuuksiltaan ja suorituskykyvaatimuksiltaan pystyy vastaamaan tutkimuksen asettamiin vaatimuksiin.",
""
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