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                "We will purchase a mass spectrometry imaging instrument for spatial multiomics analyses combining IHC with untargeted identification and characterization of endogenous molecules, and for ESI applications utilizing ion mobility separation to derive information on the three-dimensional structures of the analytes. timsTOF flex MALDI-2, provided by Bruker, is the only instruments in the market that meet all the specific and necessary technical requirements to fulfil the uncompromising needs of the acquiring department as follows: ",
                "\u2022 The instrument must have MALDI\/ESI dual ion source that enables switching without physical exchange of the source.",
                "\u2022 The instrument needs to be capable of fast (10 pixels\/s) and high resolution (down to 5 \u03bcm pixel size) MALDI-imaging.",
                "\u2022 The MALDI ion source must consist of a two-laser setup (MALDI-2) for improved sensitivity and ability detect multiple compound classes. ",
                "\u2022 The instrument must have a trapped ion mobility mass spectrometry (TIMS) capability to resolve isobaric compounds and to provide Collision Cross Section (CCS) values with high reproducibility (relative standard deviation \u2264 0.5%)",
                "\u2022 The instrument needs to have dual-TIMS technology to enable parallel accumulation and serial fragmentation (PASEF) -based methods.",
                "\u2022 The instrument must provide competitive performance (>120Hz Acquisition speed with high duty cycle, 60000 mass resolution independent of MS or MS\/MS sequencing speed), and pre-defined methods utilizing both m\/z and ion mobility data, for DDA, DIA, and PRM proteomics applications.",
                "",
                "According to the Act on Public Procurement and Concession Contracts (1397\/2016) section 40 when only a certain supplier can implement the procurement for a technical reason, provided also that there are no reasonable alternatives or substitute solutions, and that the absence of competition is not due to an artificial narrowing of the terms and conditions of the procurement, the contract may be awarded only to a particular supplier, Contracting authorities may award public contracts by a direct award. ",
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